{"id":2180,"date":"2024-11-12T15:01:05","date_gmt":"2024-11-12T15:01:05","guid":{"rendered":"https:\/\/live-champs-new.pantheonsite.io\/?post_type=resource&#038;p=2180"},"modified":"2024-11-17T18:42:45","modified_gmt":"2024-11-17T18:42:45","slug":"a-stillbirth-caused-by-a-notifiable-infectious-condition-that-suggested-public-health-action","status":"publish","type":"resource","link":"https:\/\/champshealth.org\/resource\/a-stillbirth-caused-by-a-notifiable-infectious-condition-that-suggested-public-health-action\/","title":{"rendered":"A stillbirth caused by a notifiable infectious condition that suggested public health action"},"content":{"rendered":"\n<div class=\"wp-block-cover alignfull is-light page-header-standard\"><span aria-hidden=\"true\" class=\"wp-block-cover__background has-background-dim-70 has-background-dim\" style=\"background-color:#b796ca\"><\/span><img loading=\"lazy\" decoding=\"async\" width=\"1650\" height=\"1100\" class=\"wp-block-cover__image-background wp-image-2185\" alt=\"\" src=\"https:\/\/live-champs-new.pantheonsite.io\/wp-content\/uploads\/2024\/11\/2017-3014-HE-20X-Placenta.png\" data-object-fit=\"cover\" srcset=\"https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-HE-20X-Placenta.png 1650w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-HE-20X-Placenta-300x200.png 300w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-HE-20X-Placenta-1024x683.png 1024w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-HE-20X-Placenta-768x512.png 768w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-HE-20X-Placenta-1536x1024.png 1536w\" sizes=\"auto, (max-width: 1650px) 100vw, 1650px\" \/><div class=\"wp-block-cover__inner-container is-layout-flow wp-block-cover-is-layout-flow\">\n<p class=\"has-text-align-center\">CHAMPS RESOURCES<\/p>\n\n\n\n<h2 class=\"wp-block-heading text-center\">CHAMPS Resources<\/h2>\n<\/div><\/div>\n\n\n<div class=\"publication-meta\"> \n\n<p class=\"publication-date\"> October 14, 2018 <\/p>\n\n<div class=\"publication-share\">\n\n<span class=\"share\">Share: <\/span> <ul> \n\n<li class=\"publication-share-facebook\"> <a href=\"\"> <i class=\"fa fa-facebook\"> <\/i> <\/a><\/li>\n<li class=\"publication-share-facebook\"> <a href=\"\"> <i class=\"fa-brands fa-x-twitter\"><\/i> <\/a><\/li>\n<li class=\"publication-share-instagran\"> <a href=\"\"> <i class=\"fa-brands fa-instagram\"><\/i> <\/a><\/li>\n\n<\/ul>\n <\/div>\n <\/div>\n\n <p class=\"publication-title\">A stillbirth caused by a notifiable infectious condition that suggested public health action <\/p>\n\n\n<div class=\"wp-block-group content-white\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<p class=\"has-text-align-left w-65 margin-auto\">A stillborn baby boy was delivered at the hospital to a mother who was HIV positive and pregnant with twins. The mother was started on highly active antiretroviral therapy (HAART) in her second trimester. She went in to labor 5 weeks early, at 35 weeks. The other twin was born alive.&nbsp;<strong>At the time of delivery, the cause of stillbirth was unknown<\/strong>.<\/p>\n\n\n\n<p>An interview with family members after the stillbirth (a verbal autopsy) indicated that&nbsp;<strong>the mother thought the baby suffered an injury during delivery<\/strong>&nbsp;that led to the stillbirth.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Uncovering the cause<\/h2>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p>Blood, spinal fluid, and tissues of the stillborn&nbsp;<strong>baby tested positive for&nbsp;<em>Treponema pallidum<\/em>, the bacteria that causes Syphilis<\/strong>.<\/p>\n\n\n\n<p>Syphilis is a serious bacterial infection that is sexually transmitted and can be passed from a pregnant mother to her unborn baby. It is a cause of stillbirth.&nbsp;Because syphilis is treatable with penicillin, the&nbsp;<a href=\"http:\/\/apps.who.int\/iris\/bitstream\/handle\/10665\/259003\/9789241550093-eng.pdf;jsessionid=AB26093BE363DC9FD6DC5B0095D2B1C8?sequence=1\">World Health Organization recommends<\/a>&nbsp;that all women be screened for syphilis during pregnancy.<\/p>\n\n\n\n<p>Pathology confirmed that\u00a0<strong>Syphilis was the cause of the stillbirth<\/strong>\u00a0with the bacteria,\u00a0<em>Treponema pallidum<\/em>, found in all of the types of tissues collected \u2013 liver, lung, brain, placenta, and umbilical cord.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pathology images of&nbsp;<em>Treponema pallidum<\/em><\/h2>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/live-champs-new.pantheonsite.io\/wp-content\/uploads\/2024\/11\/2017-3014-HE-20X-Placenta-1024x683.png\" alt=\"\" class=\"wp-image-2185\" srcset=\"https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-HE-20X-Placenta-1024x683.png 1024w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-HE-20X-Placenta-300x200.png 300w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-HE-20X-Placenta-768x512.png 768w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-HE-20X-Placenta-1536x1024.png 1536w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-HE-20X-Placenta.png 1650w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\">Karyorrhexis in placental chorionic villi<\/figcaption><\/figure><\/div>\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/live-champs-new.pantheonsite.io\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-63X-T.-pallidum-Placenta-arrow-1024x683.png\" alt=\"\" class=\"wp-image-2190\" srcset=\"https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-63X-T.-pallidum-Placenta-arrow-1024x683.png 1024w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-63X-T.-pallidum-Placenta-arrow-300x200.png 300w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-63X-T.-pallidum-Placenta-arrow-768x512.png 768w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-63X-T.-pallidum-Placenta-arrow-1536x1024.png 1536w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-63X-T.-pallidum-Placenta-arrow.png 1650w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\">Treponema spirochete seen in the placenta by immunohistochemistry (arrow)<\/figcaption><\/figure><\/div>\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"630\" src=\"https:\/\/live-champs-new.pantheonsite.io\/wp-content\/uploads\/2024\/11\/2017-3014-HE-10X-Placenta-1024x630.png\" alt=\"\" class=\"wp-image-2182\" srcset=\"https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-HE-10X-Placenta-1024x630.png 1024w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-HE-10X-Placenta-300x185.png 300w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-HE-10X-Placenta-768x472.png 768w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-HE-10X-Placenta.png 1481w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\">Umbilical cord \u2013 Wharton\u2019s jelly without inflammation<\/figcaption><\/figure><\/div>\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/live-champs-new.pantheonsite.io\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-40X-T.-pallidum-Umbilical-cord-1024x683.png\" alt=\"\" class=\"wp-image-2188\" srcset=\"https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-40X-T.-pallidum-Umbilical-cord-1024x683.png 1024w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-40X-T.-pallidum-Umbilical-cord-300x200.png 300w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-40X-T.-pallidum-Umbilical-cord-768x512.png 768w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-40X-T.-pallidum-Umbilical-cord-1536x1024.png 1536w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-40X-T.-pallidum-Umbilical-cord.png 1650w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\">Numerous Treponema spirochetes seen in Wharton\u2019s jelly of the umbilical cord by immunohistochemistry<\/figcaption><\/figure><\/div>\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"633\" src=\"https:\/\/live-champs-new.pantheonsite.io\/wp-content\/uploads\/2024\/11\/2017-3014-HE-20X-Lung-1024x633.png\" alt=\"\" class=\"wp-image-2184\" srcset=\"https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-HE-20X-Lung-1024x633.png 1024w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-HE-20X-Lung-300x186.png 300w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-HE-20X-Lung-768x475.png 768w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-HE-20X-Lung.png 1473w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\">Premature lung<\/figcaption><\/figure><\/div>\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/live-champs-new.pantheonsite.io\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-40X-T.-pallidum-Lung-1024x683.png\" alt=\"\" class=\"wp-image-2187\" srcset=\"https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-40X-T.-pallidum-Lung-1024x683.png 1024w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-40X-T.-pallidum-Lung-300x200.png 300w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-40X-T.-pallidum-Lung-768x512.png 768w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-40X-T.-pallidum-Lung-1536x1024.png 1536w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-40X-T.-pallidum-Lung.png 1650w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\">Scattered Treponema spirochetes seen in the lung by immunohistochemistry (arrows)<\/figcaption><\/figure><\/div>\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/live-champs-new.pantheonsite.io\/wp-content\/uploads\/2024\/11\/2017-3014-HE-20X-Liver-arrow-1024x683.png\" alt=\"\" class=\"wp-image-2183\" srcset=\"https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-HE-20X-Liver-arrow-1024x683.png 1024w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-HE-20X-Liver-arrow-300x200.png 300w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-HE-20X-Liver-arrow-768x512.png 768w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-HE-20X-Liver-arrow-1536x1024.png 1536w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-HE-20X-Liver-arrow.png 1650w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\">Autolyzed liver with extramedullary hematopoiesis (arrows)<\/figcaption><\/figure><\/div>\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/live-champs-new.pantheonsite.io\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-63X-T.-pallidum-Liver-1024x683.png\" alt=\"\" class=\"wp-image-2189\" srcset=\"https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-63X-T.-pallidum-Liver-1024x683.png 1024w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-63X-T.-pallidum-Liver-300x200.png 300w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-63X-T.-pallidum-Liver-768x512.png 768w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-63X-T.-pallidum-Liver-1536x1024.png 1536w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-63X-T.-pallidum-Liver.png 1650w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\">Abundant Treponema spirochetes seen in the liver by immunohistochemistry<\/figcaption><\/figure><\/div>\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"633\" src=\"https:\/\/live-champs-new.pantheonsite.io\/wp-content\/uploads\/2024\/11\/2017-3014-HE-10X-Brain-transnasal-1024x633.png\" alt=\"\" class=\"wp-image-2181\" srcset=\"https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-HE-10X-Brain-transnasal-1024x633.png 1024w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-HE-10X-Brain-transnasal-300x186.png 300w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-HE-10X-Brain-transnasal-768x475.png 768w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-HE-10X-Brain-transnasal.png 1473w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\">Brain without histopathologic abnormalities<\/figcaption><\/figure><\/div>\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/live-champs-new.pantheonsite.io\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-40X-T.-pallidum-Brain-transnasal-arrow-1024x683.png\" alt=\"\" class=\"wp-image-2186\" srcset=\"https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-40X-T.-pallidum-Brain-transnasal-arrow-1024x683.png 1024w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-40X-T.-pallidum-Brain-transnasal-arrow-300x200.png 300w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-40X-T.-pallidum-Brain-transnasal-arrow-768x512.png 768w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-40X-T.-pallidum-Brain-transnasal-arrow-1536x1024.png 1536w, https:\/\/champshealth.org\/wp-content\/uploads\/2024\/11\/2017-3014-IHC-40X-T.-pallidum-Brain-transnasal-arrow.png 1650w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\">Many Treponema spirochetes seen in the brain by immunohistochemistry (arrows)<\/figcaption><\/figure><\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-group content-white\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<p class=\"has-text-align-left w-65 margin-auto\">Family follow up<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p><strong>The CHAMPS team provided these results to the mother to ensure that she and her living baby were treated for syphilis.<\/strong>&nbsp;Neither of them had developed symptoms and both were doing well.<\/p>\n\n\n\n<p><strong>This mother now knows what happened to the baby she lost even before its birth<\/strong>, and&nbsp;she and her living baby are healthier as a result.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Public Health Implications<\/h2>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p>The local CHAMPS team learned that there had been a<strong>&nbsp;shortage of syphilis testing kits<\/strong>&nbsp;that prevented&nbsp;this mother from having the recommended prenatal tests, even though she had regular visits with her doctor during her pregnancy. The CHAMPS team identified a problem that local health authorities will be able to correct within their health system, preventing other families from experiencing problems with getting syphilis testing in the future.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"has-text-align-center w-65 margin-auto\"><strong>Interested in CHAMPS\u2019s pathology slide images?<\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center w-65 margin-auto\"><strong><br><\/strong>Email\u00a0<a href=\"mailto:data@champshealth.org\">data@champshealth.org<\/a>\u00a0to learn more!\u00a0<\/p>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>A stillborn baby boy was delivered at the hospital to a mother who was HIV positive and pregnant with twins. The mother was started on highly active antiretroviral therapy (HAART) in her second trimester. She went in to labor 5 weeks early, at 35 weeks. The other twin was born alive.&nbsp;At the time of delivery, [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/champshealth.org\/resource\/a-stillbirth-caused-by-a-notifiable-infectious-condition-that-suggested-public-health-action\/\">Read More&#8230;<span class=\"screen-reader-text\"> from A stillbirth caused by a notifiable infectious condition that suggested public health action<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":2191,"parent":0,"template":"","meta":{"_acf_changed":false,"footnotes":""},"tags":[],"resource_category":[9],"class_list":["post-2180","resource","type-resource","status-publish","has-post-thumbnail","hentry","resource_category-case-example"],"acf":[],"_links":{"self":[{"href":"https:\/\/champshealth.org\/wp-json\/wp\/v2\/resource\/2180","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/champshealth.org\/wp-json\/wp\/v2\/resource"}],"about":[{"href":"https:\/\/champshealth.org\/wp-json\/wp\/v2\/types\/resource"}],"author":[{"embeddable":true,"href":"https:\/\/champshealth.org\/wp-json\/wp\/v2\/users\/3"}],"version-history":[{"count":2,"href":"https:\/\/champshealth.org\/wp-json\/wp\/v2\/resource\/2180\/revisions"}],"predecessor-version":[{"id":2243,"href":"https:\/\/champshealth.org\/wp-json\/wp\/v2\/resource\/2180\/revisions\/2243"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/champshealth.org\/wp-json\/wp\/v2\/media\/2191"}],"wp:attachment":[{"href":"https:\/\/champshealth.org\/wp-json\/wp\/v2\/media?parent=2180"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/champshealth.org\/wp-json\/wp\/v2\/tags?post=2180"},{"taxonomy":"resource_category","embeddable":true,"href":"https:\/\/champshealth.org\/wp-json\/wp\/v2\/resource_category?post=2180"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}